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Prefrontal Cortex and Schizophrenia

Yuan-ye MA

Institute of Biophysics
Chinese Academy of Sciences, China


Prefrontal dysfunction and schizophrenia have a close relationship, however, for the specific mechanisms we still do not know. In the study of the PCP-induced schizophrenia-like behavior in monkeys, we found that the effects of PCP on the orbital cortex are longer than that on the dorso-lateral prefrontal area. We also found that the PCP led to the prefrontal myelination accelerated in juvenile macaque.

Short Bio

YuanYe Ma is a professor and director of Laboratory of Primate Cognitive Neuroscience, Kunming Institute of Zoology, Chinese Academy of Sciences and also a professor in State Key Laboratory of Brain and Cognitive Science in Institute of Biophysics, Chinese Academy of Science, He focuses on the cognitive function of the prefrontal cortex and the prefrontal mechanisms of some related mental disorders, such as schizophrenia , depression and autism.

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Last updated: December 18, 2013